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Our understanding of the extent and nature of resistance in P. vivax parasites is very limited. WWARN's new chloroquine resistant P. vivax literature review gathers all the evidence together on the global extent of reduced P. vivax susceptibility to the frontline antimalarial chloroquine. It highlights the diversity of methodologies that have been used to quantify therapeutic efficacy and summarises the current geographical extent and absence of data for reduced susceptibility to P. vivax.
This literature review is just one of many reviews and downloadable databases available:
- The ACT and Parasite Clearance Review delves through more than 10 years of published data to look for trends in early parasitological response following treatment with an artemisinin anti-malarial regimen
- The Pharmacology Publication Database provides a comprehensive compilation of all antimalarial pharmacokinetic and pharmacodynamics studies conducted and published since 1934
- The Primaquine Review explores published studies since 1950 of the use of primaquine regimens for preventing P. vivax relapse
Read a full summary of the these literature reviews and databases.
Related article: Price RN, von Seidlein L, Valecha N, et al. The global extent of chloroquine resistant plasmodium vivax: a systematic review and meta-analysis. Lancet Infectious Diseases; DOI S1473-3099(14)70855-2.